Cast & Crew zu Wie das Leben so spielt
| George Simmons | Adam Sandler | |
| Ira Wright | Seth Rogen | |
| Laura | Leslie Mann | |
| Clarke | Eric Bana | |
| Leo Koenig | Jonah Hill | |
| Mark Taylor Jackson | Jason Schwartzman | |
| Daisy | Aubrey Plaza | |
| Mable | Maude Apatow | |
| Ingrid | Iris Apatow | |
| Chuck | RZA | |
| Randy | Aziz Ansari | |
| Dr. Lars | Torsten Voges | |
| Dr. Stevens | Allan Wasserman | |
| Himself | Rod Man | |
| Comedy & Magic Manager | Wayne Federman | |
| MySpace Escort | Mike O'Connell | |
| Himself | James Taylor | |
| Dawn | Nicole Ari Parker | |
| Mandy | Nydia McFadden | |
| Himself | Andy Dick | |
| Himself | Charles Fleischer | |
| Lisa | Nicol Paone | |
| George's Dad | George Coe | |
| Himself | Budd Friedman | |
| Himself | Monty Hoffman | |
| Herself | Carol Leifer | |
| Himself | Paul Reiser | |
| Himself | Mark Schiff | |
| Himself | George Wallace | |
| Himself | Norm MacDonald | |
| Himself | Dave Attell | |
| Herself | Sarah Silverman | |
| George's Agent | Bryan Batt | |
| Rachel | Maggie Siff | |
| Himself | Eminem | |
| Himself | Ray Romano | |
| Re-Do Guy | Justin Long | |
| Chuck's Wife | Qiana Chase | |
| Regie |
Judd Apatow |
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| Buch |
Judd Apatow |
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| Kamera |
Janusz Kaminski |
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| Schnitt |
Craig Alpert Brent White |
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| Musik |
Michael Andrews Jason Schwartzman |
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